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USP12 Antikörper (N-Term)

USP12 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN357542
  • Target Alle USP12 Antikörper anzeigen
    USP12 (Ubiquitin Specific Peptidase 12 (USP12))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 42
    • 36
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 50
    • 4
    Kaninchen
    Klonalität
    • 53
    • 1
    Polyklonal
    Konjugat
    • 23
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser USP12 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 34
    • 9
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific to USP12 (N-term).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human USP12.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product USP12 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    USP12 (Ubiquitin Specific Peptidase 12 (USP12))
    Andere Bezeichnung
    USP12 (USP12 Produkte)
    Synonyme
    UBH1 antikoerper, USP12L1 antikoerper, usp12 antikoerper, USP12P1 antikoerper, sb:eu882 antikoerper, wu:fi09d12 antikoerper, Ubh1 antikoerper, ubh1 antikoerper, usp12l1 antikoerper, ubiquitin specific peptidase 12 antikoerper, ubiquitin specific peptidase 12a antikoerper, ubiquitin specific peptidase 12 L homeolog antikoerper, ubiquitin specific peptidase 12 S homeolog antikoerper, USP12 antikoerper, usp12 antikoerper, Usp12 antikoerper, usp12a antikoerper, usp12.L antikoerper, usp12.S antikoerper
    Hintergrund
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 12, UBH1, USP12L1, Ubiquitin carboxyl-terminal hydrolase 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12
    Molekulargewicht
    41201 Da
    Gen-ID
    219333, 5874
    UniProt
    O75317
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