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SNURF Antikörper (Middle Region)

SNURF Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN357983
  • Target Alle SNURF Antikörper anzeigen
    SNURF (SNRPN Upstream Reading Frame (SNURF))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human
    Wirt
    • 3
    • 2
    Kaninchen
    Klonalität
    • 5
    Polyklonal
    Konjugat
    • 5
    Dieser SNURF Antikörper ist unkonjugiert
    Applikation
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects SNURF (Center).
    Aufreinigung
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human SNURF.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SNURF Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western Blot: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    SNURF (SNRPN Upstream Reading Frame (SNURF))
    Andere Bezeichnung
    SNURF (SNURF Produkte)
    Synonyme
    2410045I01Rik antikoerper, Snrpn antikoerper, SNRPN upstream reading frame antikoerper, small nuclear ribonucleoprotein polypeptide N antikoerper, SNURF antikoerper, SNRPN antikoerper, Snurf antikoerper
    Hintergrund
    SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.Synonyms: SNRPN upstream reading frame protein
    Molekulargewicht
    8412 Da (Theoretical pI: 10.58. WB band detected at approx 30kDa).
    Gen-ID
    8926, 9606
    UniProt
    Q9Y675
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