IRS2 Antikörper (pTyr978)
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- Target Alle IRS2 Antikörper anzeigen
- IRS2 (Insulin Receptor Substrate 2 (IRS2))
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Bindungsspezifität
- pTyr978
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IRS2 Antikörper ist unkonjugiert
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Applikation
- Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects IRS2 pTyr978.
- Aufreinigung
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IRS2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- IRS2 (Insulin Receptor Substrate 2 (IRS2))
- Andere Bezeichnung
- IRS2 (IRS2 Produkte)
- Hintergrund
- Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.Synonyms: IRS-2, Insulin receptor substrate 2
- Molekulargewicht
- 137204 Da
- Gen-ID
- 8660, 9606
- UniProt
- Q9Y4H2
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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