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MEK1 Antikörper (pSer222)
MAP2K1
Reaktivität: Human
EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-MEK1 Antikörper
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Target
Alle MEK1 (MAP2K1) Antikörper anzeigen
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Bindungsspezifität
Alle Epitope für MEK1 Antikörper
pSer222
Reaktivität
Alle Reaktivitäten für MEK1 Antikörper
Human
Wirt
Alle Wirte für MEK1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MEK1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für MEK1 Antikörper
Dieser MEK1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MEK1 Antikörper
Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to MEK1 pSer222.
Aufreinigung
Protein A column, followed by two-step phosphospecific peptide affinity purification
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S222 of human MEK1.
Isotyp
Ig Fraction
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Discover our top product MAP2K1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Details zu MEK1
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Target
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Andere Bezeichnung
MAP2K1 (MAP2K1 Produkte )
Synonyme
Mek1 antikoerper, CFC3 antikoerper, MAPKK1 antikoerper, MEK1 antikoerper, MKK1 antikoerper, PRKMK1 antikoerper, MEKK1 antikoerper, Prkmk1 antikoerper, mek-2 antikoerper, si:ch211-242m18.2 antikoerper, wu:fj56a12 antikoerper, wu:fj61b01 antikoerper, zgc:56557 antikoerper, ATMEK1 antikoerper, F20B18.180 antikoerper, F20B18_180 antikoerper, MAP kinase/ ERK kinase 1 antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antikoerper, NMAPKK antikoerper, MEK antikoerper, mitogen activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 L homeolog antikoerper, MAP kinase/ ERK kinase 1 antikoerper, Map2k1 antikoerper, MAP2K1 antikoerper, map2k1.L antikoerper, map2k1 antikoerper, MEK1 antikoerper
Hintergrund
MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.Synonyms: Dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1, MAPK/ERK kinase 1, MAPKK 1, MEK1, PRKMK1
Gen-ID
5604, 9606
UniProt
Q02750
Pathways
MAPK Signalweg , RTK Signalweg , Interferon-gamma Pathway , Fc-epsilon Rezeptor Signalübertragung , Neurotrophin Signalübertragung , Activation of Innate immune Response , Toll-Like Receptors Cascades , Autophagie , Signaling of Hepatocyte Growth Factor Receptor , BCR Signaling
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