LRP6 Antikörper (C-Term)

Produktnummer ABIN358636

Produktdetails anti-LRP6 Antikörper

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to LRP6.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human LRP6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu LRP6

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Andere Bezeichnung: LRP6 (LRP6 Produkte)

Synonyme: lrp6-A antikoerper, Xlrp6 antikoerper, adcad2 antikoerper, lrp6 antikoerper, LRP6 antikoerper, ADCAD2 antikoerper, C030016K15Rik antikoerper, Cd antikoerper, Gw antikoerper, LDL receptor related protein 6 antikoerper, LDL receptor related protein 6 L homeolog antikoerper, LDL receptor related protein 6 S homeolog antikoerper, low density lipoprotein receptor-related protein 6 antikoerper, low-density lipoprotein receptor-related protein 6 antikoerper, LRP6 antikoerper, lrp6.L antikoerper, lrp6.S antikoerper, lrp6 antikoerper, Lrp6 antikoerper, LOC590395 antikoerper

Hintergrund: LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.Synonyms: LRP-6, Low-density lipoprotein receptor-related protein 6

Gen-ID: 4040, 9606

UniProt: O75581

Pathways: WNT Signalweg, Tube Formation