MAP3K12 Antikörper (C-Term)

Produktnummer ABIN359408

Produktdetails anti-MAP3K12 Antikörper

Target: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects MAP3K12 at C-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ZPK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu MAP3K12

Target: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Andere Bezeichnung: MAP3K12 (MAP3K12 Produkte)

Synonyme: DLK antikoerper, MEKK12 antikoerper, MUK antikoerper, ZPK antikoerper, ZPKP1 antikoerper, PK antikoerper, Zpk antikoerper, zgc:77370 antikoerper, MGC151798 antikoerper, dlk antikoerper, map3k12 antikoerper, map3k12a antikoerper, mekk12 antikoerper, muk antikoerper, zpk antikoerper, zpkp1 antikoerper, DKFZp459K2433 antikoerper, map3k12-a antikoerper, map3k12-b antikoerper, map3k12b antikoerper, mitogen-activated protein kinase kinase kinase 12 antikoerper, mitogen activated protein kinase kinase kinase 12 antikoerper, mitogen-activated protein kinase kinase kinase 12 S homeolog antikoerper, mitogen-activated protein kinase kinase kinase 12 L homeolog antikoerper, MAP3K12 antikoerper, Map3k12 antikoerper, map3k12 antikoerper, map3k12.S antikoerper, map3k12.L antikoerper

Hintergrund: ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.Synonyms: Dual leucine zipper bearing kinase, Leucine-zipper protein kinase, MAPK-upstream kinase, Mitogen-activated protein kinase kinase kinase 12, Mixed lineage kinase

Molekulargewicht: 93188 Da

Gen-ID: 7786, 9606

UniProt: Q12852

Pathways: MAPK Signalweg