NAE1 Antikörper (C-Term)

Produktnummer ABIN359509

Produktdetails anti-NAE1 Antikörper

Target: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects NAE1 (APPBP1) at C-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human APPBP1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry on paraffin sections 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu NAE1

Target: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Andere Bezeichnung: APPBP1 (NAE1 Produkte)

Synonyme: APPBP1 antikoerper, CG7828 antikoerper, Dmel\\CG7828 antikoerper, anon-WO0140519.225 antikoerper, dAPP-BP1 antikoerper, dAPPBP1 antikoerper, A-116A10.1 antikoerper, ula-1 antikoerper, Appbp1 antikoerper, 59kDa antikoerper, appbp1 antikoerper, zgc:66148 antikoerper, beta-Amyloid precursor protein binding protein 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 S homeolog antikoerper, nedd8 activating enzyme E1 subunit 1 antikoerper, NEDD8-activating enzyme E1 regulatory subunit antikoerper, APP-BP1 antikoerper, NAE1 antikoerper, Nae1 antikoerper, nae1.S antikoerper, nae1 antikoerper, ula-1 antikoerper

Hintergrund: APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.Synonyms: Amyloid beta precursor protein-binding protein 1, Amyloid protein-binding protein 1, HPP1, NAE1

Molekulargewicht: 60252 Da

Gen-ID: 8883, 9606

UniProt: Q13564