DCXR Antikörper (Middle Region)

Produktnummer ABIN359606

Produktdetails anti-DCXR Antikörper

Target: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCXR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse DCXR. Other species not tested.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of Human DCXR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000
Western blotting: 1/50 - 1/100
Immunohistochemistry on Paraffin Sections: 1/50-1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu DCXR

Target: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Andere Bezeichnung: L-Xylulose Reductase (DCXR Produkte)

Hintergrund: DCXR is an enzyme that has both diacetyl reductase and L-xylulose reductase activities. Function: Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. Cellular Location: Membrane, Peripheral membrane protein (By similarity). Note=Probably recruited to membranes via an interaction with phosphatidylinositol (By similarity). Tissue Location: Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.Synonyms: Carbonyl reductase II, DCXR, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, P34H, Sperm surface protein P34H, XR

Molekulargewicht: 25913 Da (calculated)

Gen-ID: 51181, 9606

UniProt: Q7Z4W1

Pathways: Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process