MAPK4 Antikörper (C-Term)

Produktnummer ABIN359633

Produktdetails anti-MAPK4 Antikörper

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to ERK4.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ERK4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MAPK4

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Andere Bezeichnung: MAPK4 / ERK4 (MAPK4 Produkte)

Synonyme: ERK-4 antikoerper, ERK3 antikoerper, Erk4 antikoerper, MAPK 4 antikoerper, PRKM4 antikoerper, p63MAPK antikoerper, A330097D03Rik antikoerper, Erk3 antikoerper, Prkm4 antikoerper, p63Mapk antikoerper, erk4 antikoerper, wu:fi27d11 antikoerper, zgc:55498 antikoerper, ATMPK4 antikoerper, F2N1.1 antikoerper, F2N1_1 antikoerper, MAP kinase 4 antikoerper, mitogen-activated protein kinase 4 antikoerper, MAP kinase 4 antikoerper, MAPK4 antikoerper, Mapk4 antikoerper, mapk4 antikoerper, MPK4 antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.Synonyms: Extracellular signal-regulated kinase 4, MAP kinase isoform p63, Mitogen-activated protein kinase 4, p63-MAPK

Gen-ID: 5596, 9606

UniProt: P31152

Pathways: MAPK Signalweg