ANTXR1 Antikörper (Tyr382)
-
- Target Alle ANTXR1 Antikörper anzeigen
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
-
Bindungsspezifität
- AA 365-394, Tyr382
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ANTXR1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizesANTXR1.
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 365~394 amino acids surrounding Tyr382 of Human ANTXR1.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ANTXR1 Primärantikörper
-
-
- Applikationshinweise
-
ELISA: 1/1,000. Western blotting: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
- Target
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- Andere Bezeichnung
- Anthrax Toxin Receptor 1 (ANTXR1 Produkte)
- Synonyme
- ANTXR1 antikoerper, ATR antikoerper, TEM8 antikoerper, 2310008J16Rik antikoerper, 2810405N18Rik antikoerper, Antrx1 antikoerper, Tem8 antikoerper, anthrax toxin receptor 1 antikoerper, ANTXR1 antikoerper, Antxr1 antikoerper
- Hintergrund
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
- Gen-ID
- 84168, 9606
- UniProt
- Q9H6X2
-