BACE1 Antikörper (Ser498)
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- Target Alle BACE1 Antikörper anzeigen
- BACE1 (Beta-secretase 1 (BACE1))
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Bindungsspezifität
- Ser498
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BACE1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody reacts to BACE around Ser498.
- Aufreinigung
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S498 of human BACE.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product BACE1 Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- BACE1 (Beta-secretase 1 (BACE1))
- Andere Bezeichnung
- BACE1 (BACE1 Produkte)
- Synonyme
- ASP2 antikoerper, BACE antikoerper, HSPC104 antikoerper, C76936 antikoerper, Bace antikoerper, MGC145931 antikoerper, BACE1 antikoerper, zgc:77409 antikoerper, beta-secretase 1 antikoerper, beta-site APP cleaving enzyme 1 antikoerper, beta-site APP-cleaving enzyme 1 antikoerper, BACE1 antikoerper, Bace1 antikoerper, bace1 antikoerper
- Hintergrund
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Synonyms: ASP2, Aspartyl protease 2, BACE, BACE-1, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2
- Gen-ID
- 23621, 9606
- UniProt
- P56817
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