TBK1 Antikörper (Ser172)
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- Target Alle TBK1 Antikörper anzeigen
- TBK1 (TANK-Binding Kinase 1 (TBK1))
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Bindungsspezifität
- Ser172
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody reacts to TBK.
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S172 of human TBK.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TBK1 Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- Andere Bezeichnung
- TBK1 (TBK1 Produkte)
- Synonyme
- nak antikoerper, t2k antikoerper, TBK1 antikoerper, wu:fk70c05 antikoerper, zgc:136548 antikoerper, NAK antikoerper, T2K antikoerper, 1200008B05Rik antikoerper, AI462036 antikoerper, AW048562 antikoerper, TANK binding kinase 1 L homeolog antikoerper, TANK binding kinase 1 antikoerper, TANK-binding kinase 1 antikoerper, tbk1.L antikoerper, TBK1 antikoerper, tbk1 antikoerper, Tbk1 antikoerper
- Hintergrund
- The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.Synonyms: NAK, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1
- Gen-ID
- 29110, 9606
- UniProt
- Q9UHD2
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom
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