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PKN3 Antikörper (C-Term)

PKN3 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN360331
  • Target Alle PKN3 Antikörper anzeigen
    PKN3 (Protein Kinase N3 (PKN3))
    Bindungsspezifität
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 26
    • 22
    • 1
    Human
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PKN3 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 25
    • 9
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to PKN beta.
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PKN beta.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PKN3 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PKN3 (Protein Kinase N3 (PKN3))
    Andere Bezeichnung
    PKN3 (PKN3 Produkte)
    Synonyme
    prkcl2 antikoerper, wu:fb92a02 antikoerper, si:dkey-202g15.3 antikoerper, PKN3 antikoerper, RP11-545E17.1 antikoerper, AW209115 antikoerper, BC034126 antikoerper, LRRGT00147 antikoerper, protein kinase N3 antikoerper, pkn3 antikoerper, PKN3 antikoerper, Pkn3 antikoerper
    Hintergrund
    PKN3, a protein kinase C-related molecule, mediates malignant cell growth downstream of activated PI3K. PKN3 is required for invasive prostate cell growth as assessed by 3D cell culture assays and in an orthotopic mouse tumor model by inducible expression of short hairpin RNA (shRNA). PKN3 is regulated by PI3K at both the expression level and the catalytic activity level. Therefore, PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of PI3K.Synonyms: PKN beta, PKN-beta, PKNBETA, Protein-kinase C-related kinase 3, Serine/threonine-protein kinase N3
    Gen-ID
    29941, 9606
    UniProt
    Q6P5Z2
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