MAP3K14 Antikörper (Middle Region)

Produktnummer ABIN360384

Produktdetails anti-MAP3K14 Antikörper

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to NFkB Inducing Kinase (NIK).

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human NIK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Andere Bezeichnung: MAP3K14 (MAP3K14 Produkte)

Synonyme: FTDCR1B antikoerper, HS antikoerper, HSNIK antikoerper, NIK antikoerper, F23F1.4 antikoerper, F23F1_4 antikoerper, mitogen-activated protein kinase kinase kinase 14 antikoerper, Nik antikoerper, aly antikoerper, mitogen-activated protein kinase kinase kinase 14 antikoerper, MAP3K14 antikoerper, Map3k14 antikoerper, MAPKKK14 antikoerper

Hintergrund: NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.Synonyms: Mitogen-activated protein kinase kinase kinase 14, NF-kappa beta-inducing kinase, Serine/threonine-protein kinase NIK

Gen-ID: 9020

NCBI Accession: NP_003945

UniProt: Q99558

Pathways: NF-kappaB Signalweg, T-Zell Rezeptor Signalweg