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PIK3R2 Antikörper (Tyr467)

PI3K p85b Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN360466
  • Target Alle PIK3R2 (PI3K p85b) Antikörper anzeigen
    PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr467
    Reaktivität
    • 108
    • 55
    • 26
    • 17
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 103
    • 6
    Kaninchen
    Klonalität
    • 95
    • 14
    Polyklonal
    Konjugat
    • 46
    • 8
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser PIK3R2 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 45
    • 31
    • 16
    • 13
    • 13
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to PIK3R2.
    Aufreinigung
    Protein A column, followed by peptide affinity purification
    Immunogen
    This antibody is generated from rabbits immunized with a peptide corresponding to amino acid residues surrounding Y467 of human PIK3R2.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PI3K p85b Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
    Andere Bezeichnung
    PIK3R2 (PI3K p85b Produkte)
    Synonyme
    MPPH antikoerper, P85B antikoerper, p85 antikoerper, p85-BETA antikoerper, pik3r2 antikoerper, MGC80449 antikoerper, p85beta antikoerper, phosphoinositide-3-kinase regulatory subunit 2 antikoerper, phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) antikoerper, phosphoinositide-3-kinase, regulatory subunit 2 (beta) antikoerper, PIK3R2 antikoerper, pik3r2 antikoerper, Pik3r2 antikoerper
    Hintergrund
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.Synonyms: PI 3 Kinase p85 beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, Phosphatidylinositol 3-kinase regulatory subunit beta
    Gen-ID
    5296, 9606
    UniProt
    O00459
    Pathways
    VEGF Signaling, BCR Signaling
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