DUSP8 Antikörper (C-Term)

Produktnummer ABIN360785

Produktdetails anti-DUSP8 Antikörper

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to DUSP8.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DUSP8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu DUSP8

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Abstract: DUSP8 Produkte

Synonyme: zgc:77593 antikoerper, C11orf81 antikoerper, HB5 antikoerper, HVH-5 antikoerper, HVH8 antikoerper, 5530400B01Rik antikoerper, AI593498 antikoerper, Nttp1 antikoerper, Hb5 antikoerper, M3/6 antikoerper, DUSP8 antikoerper, dual specificity phosphatase 8 antikoerper, dual specificity phosphatase 8a antikoerper, dual specificity protein phosphatase 8 antikoerper, DUSP8 antikoerper, dusp8 antikoerper, dusp8a antikoerper, DSP8 antikoerper, Dusp8 antikoerper, LOC615727 antikoerper

Hintergrund: DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP8 inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.Synonyms: Dual specificity protein phosphatase 8

Gen-ID: 1850, 9606

UniProt: Q13202