IL20RA Antikörper (Extracellular Domain)

Produktnummer ABIN360917

Produktdetails anti-IL20RA Antikörper

Target: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Bindungsspezifität: Extracellular Domain

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL20RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects IL-20Ralpha.

Aufreinigung: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IL-20Ralpha extracellular domain.

Klon: 11C42

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL20RA

Target: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Andere Bezeichnung: IL20RA (IL20RA Produkte)

Synonyme: CRF2-8 antikoerper, IL-20R-alpha antikoerper, IL-20R1 antikoerper, IL-20RA antikoerper, E230031K19 antikoerper, interleukin 20 receptor subunit alpha antikoerper, interleukin 20 receptor, alpha antikoerper, IL20RA antikoerper, Il20ra antikoerper

Hintergrund: The receptor for interleukin 20 is a heterodimer of 2 orphan class II cytokine receptor subunits, IL20RA, also called ZCYTOR7, and IL20RB, also called DIRS1. Binding assays demonstrated that IL20 bound to BHK transfectants expressing both IL20RA and IL20RB, but not to untransfected cells nor to transfectants expressing either receptor subunit alone. Binding of (125)I labeled IL20 was eliminated in the presence of 100 fold excess of unlabeled IL20 but not in the presence of 100 fold excess of the unrelated cytokine, IL21. The binding data revealed 88,000 IL20 receptors per cell, with a binding affinity of approximately 1.5 nM. Both receptor subunits were expressed in skin and were dramatically upregulated in psoriatic skin.Synonyms: Cytokine receptor class-II member 8, Cytokine receptor family 2 member 8, IL-20R-alpha, IL-20R1, Interleukin-20 receptor alpha chain, ZCYTOR7

Gen-ID: 237313

NCBI Accession: NP_766374

UniProt: Q6PHB0