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NEFH Antikörper

NEFH Reaktivität: Rind (Kuh) WB, IF Wirt: Maus Monoclonal NAP4 unconjugated
Produktnummer ABIN361350
  • Target Alle NEFH Antikörper anzeigen
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Reaktivität
    • 114
    • 83
    • 64
    • 50
    • 31
    • 22
    • 12
    • 12
    • 9
    • 9
    • 9
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Rind (Kuh)
    Wirt
    • 67
    • 57
    • 8
    Maus
    Klonalität
    • 82
    • 50
    Monoklonal
    Konjugat
    • 83
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEFH Antikörper ist unkonjugiert
    Applikation
    • 81
    • 41
    • 37
    • 26
    • 26
    • 24
    • 19
    • 14
    • 13
    • 13
    • 12
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Spezifität
    Specific for the ~200k Neurofilament H protein. It recognizes phosphorylated NF-H KSP (lysine-serine-proline) type sequences. In some species there is some cross-reactivity with the related phosphorylated KSP sequences found in the related neurofilament subunit NF-M. It recognizes neurofilaments in frozen sections in tissue culture and in formalin fixed sections.
    Kreuzreaktivität
    Huhn, Säugetier
    Aufreinigung
    Protein G purified culture supernatant
    Immunogen
    Purified bovine NF-H
    Klon
    NAP4
    Isotyp
    IgG1
    Top Product
    Discover our top product NEFH Primärantikörper
  • Applikationshinweise
    Recommended Dilution: WB: 1:5,000 IF: 1:500 Quality Control: Western blots performed on each lot.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    total IgG fraction + 10 mM Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Andere Bezeichnung
    NEFH (NEFH Produkte)
    Hintergrund
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3). Anti-Neurofilament H Western blot of rat cortex lysate showing specific immunolableing of the ~ 200k NF-H protein.
    Molekulargewicht
    '200 kDa
    Gen-ID
    4744
    UniProt
    P12036
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