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NEFM Antikörper (C-Term)

Name: NEFM Antikörper (C-Term)
Brand: antibodies-online
SKU: ABIN361355
Price: 600.6 EUR
Availability: InStock

NEFM Reaktivität: Ratte WB, IF Wirt: Huhn Polyclonal unconjugated

Western blots of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein. (NEFM Antikörper (C-Term))

Western blot of rat cortical lysate showing specific immunolabeling of the ~145 kDa NF-M protein. (NEFM Antikörper (C-Term))

Immunostaining of cultured rat neurons and glia showing labeling of NF-M in red. (NEFM Antikörper (C-Term))

ISt

3 Abbildungen

(1 reference)

Produktnummer ABIN361355

Datenblatt (PDF)

Target Alle NEFM Antikörper anzeigen

NEFM (Neurofilament Triplet M Protein (NEFM))
Bindungsspezifität
16

15

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
61

44

36

8

6

6

5

5

5

5

4

4

3

2

2

1

1
Ratte
Wirt
41

23

10

1
Huhn
Klonalität
44

31
Polyklonal
Konjugat
47

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser NEFM Antikörper ist unkonjugiert
Applikation
61

21

20

15

14

13

13

11

11

9

4

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF)

Spezifität

Specific for the ~145k Neurofilament M protein.

Kreuzreaktivität

Huhn, Rind (Kuh), Human, Maus, Ratte (Rattus)

Aufreinigung

Total IgY fraction

Immunogen

Preparation containing the extreme C-terminus expressed in and purified from E. Coli

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anti-Neurofilament Triplet M Protein (NEFM) (AA 101-200) antibody
NEFM Reaktivität: Human, Ratte, Maus WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

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NEFM Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

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NEFM Reaktivität: Ratte WB, IF Wirt: Maus Monoclonal 3H11 unconjugated

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NEFM Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated

anti-Neurofilament Triplet M Protein (NEFM) (Internal Region) antibody
Verified NEFM Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated

anti-Neurofilament Triplet M Protein (NEFM) (AA 320-370) antibody
NEFM Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

total IgY fraction in PBS + 10 mM Sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C
Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).
Target

NEFM (Neurofilament Triplet M Protein (NEFM))

Andere Bezeichnung

NEFM (NEFM Produkte)

Synonyme

NEF3 antikoerper, NF-M antikoerper, NFM antikoerper, Nef3 antikoerper, Nfm antikoerper, NF160 antikoerper, NF165 antikoerper, nef-m antikoerper, nef3 antikoerper, nefm antikoerper, nf-m antikoerper, zgc:112359 antikoerper, nefm-a antikoerper, nefm-b antikoerper, neurofilament medium antikoerper, neurofilament triplet M protein antikoerper, neurofilament, medium polypeptide antikoerper, neurofilament medium polypeptide antikoerper, neurofilament medium L homeolog antikoerper, neurofilament, medium polypeptide a antikoerper, neurofilament medium S homeolog antikoerper, NEFM antikoerper, Nefm antikoerper, TVAG_582010 antikoerper, TVAG_379630 antikoerper, nefm.L antikoerper, nefma antikoerper, nefm.S antikoerper

Hintergrund

Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.

Molekulargewicht

'145 kDa

Gen-ID

24588

UniProt

P12839

Pathways

Brown Fat Cell Differentiation