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THRA Antikörper (N-Term)
THRA
Reaktivität: Human
WB
Wirt: Maus
Monoclonal
2103
unconjugated
Produktdetails anti-THRA Antikörper
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Target
Alle THRA Antikörper anzeigen
THRA
(Thyroid Hormone Receptor, alpha (THRA))
Bindungsspezifität
Alle Epitope für THRA Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für THRA Antikörper
Human
Wirt
Alle Wirte für THRA Antikörper
Maus
Klonalität
Alle Klonalitäten für THRA Antikörper
Monoklonal
Konjugat
Alle Konjugate für THRA Antikörper
Dieser THRA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für THRA Antikörper
Western Blotting (WB)
Spezifität
Specific for the ~50k TR-a1 and the ~58k TR-a2 proteins.
Kreuzreaktivität
Human, Ratte (Rattus)
Homologie
canine, mouse, non-human primate
Aufreinigung
Protein G purified culture supernatant
Immunogen
Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Klon
2103
Isotyp
IgG1
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Anwendungsinformationen
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Applikationshinweise
Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
Lagerung
-20 °C
Details zu THRA
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Target
THRA
(Thyroid Hormone Receptor, alpha (THRA))
Andere Bezeichnung
THRA (THRA Produkte )
Synonyme
AR7 antikoerper, CHNG6 antikoerper, EAR7 antikoerper, ERB-T-1 antikoerper, ERBA antikoerper, ERBA1 antikoerper, NR1A1 antikoerper, THRA1 antikoerper, THRA2 antikoerper, c-ERBA-1 antikoerper, C-ERBA-ALPHA antikoerper, TRalpha antikoerper, c-erba antikoerper, erba antikoerper, nr1a1-A antikoerper, thra-A antikoerper, thra1 antikoerper, TR[a]1 antikoerper, nr1a1 antikoerper, thra antikoerper, thral antikoerper, tra antikoerper, tra1 antikoerper, wu:fb59g07 antikoerper, Thra1 antikoerper, 6430529J03Rik antikoerper, AW259572 antikoerper, Erba antikoerper, Nr1a1 antikoerper, Rvr antikoerper, T3R[a] antikoerper, T3Ralpha antikoerper, Thra2 antikoerper, C-ERBA ALPHA1 antikoerper, Thra antikoerper, fTHRalphaA antikoerper, nr1a1-a antikoerper, thyroid hormone receptor, alpha antikoerper, thyroid hormone receptor, alpha L homeolog antikoerper, thyroid hormone receptor alpha a antikoerper, thyroid hormone receptor alpha antikoerper, thyroid hormone receptor alpha-A antikoerper, THRA antikoerper, thra.L antikoerper, thraa antikoerper, Thra antikoerper, tr-alpha antikoerper, LOC109641414 antikoerper
Hintergrund
Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TR 1 and TR 2. TRa1, TR 1 and TR 2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005). Anti-Thyroid Hormone Receptor, a1/a2-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~50k TR-a1 and the ~58k TR-a2 protein.
Molekulargewicht
50/58 kDa
Gen-ID
7067
UniProt
P10827
Pathways
Nuclear Receptor Transcription Pathway , Steroid Hormone Mediated Signaling Pathway , Sensory Perception of Sound , Cellular Response to Molecule of Bacterial Origin , Regulation of Lipid Metabolism by PPARalpha , Regulation of Muscle Cell Differentiation , Maintenance of Protein Location , Skeletal Muscle Fiber Development
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