Retinoid X Receptor beta Antikörper

Produktnummer ABIN361387

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Retinoid X Receptor beta in WB. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Retinoid X Receptor beta Antikörper (ABIN361387)

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoid X Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 147

Produktdetails anti-Retinoid X Receptor beta Antikörper

Spezifität: Specific for the ~48k RXR-( protein.

Kreuzreaktivität: Maus, Ratte (Rattus)

Aufreinigung: Protein G purified culture supernatant

Immunogen: Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Details zu Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Andere Bezeichnung: RXRB

Hintergrund: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRa, ß and (), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). Anti-Human Retinoid X Receptor Antibody, (-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RXR-ß protein.

Molekulargewicht: '48 kDa

Gen-ID: 6257

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway