Tryptophan Hydroxylase 1 Antikörper
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- Target Alle Tryptophan Hydroxylase 1 (TPH1) Antikörper anzeigen
- Tryptophan Hydroxylase 1 (TPH1)
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Reaktivität
- Kaninchen
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Wirt
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Schaf
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Klonalität
- Polyklonal
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Konjugat
- Dieser Tryptophan Hydroxylase 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Specific for the ~55k tryptophan hydroxylase protein.
- Kreuzreaktivität
- Human, Ratte (Rattus)
- Homologie
- wide variety mammalian
- Aufreinigung
- Antigen Affinity Purified from Pooled Serum
- Immunogen
- Recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE
- Top Product
- Discover our top product TPH1 Primärantikörper
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anti-Tryptophan Hydroxylase 1 (TPH1) (Internal Region) antibody
TPH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 35-62), (N-Term) antibodyTPH1 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21510 unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 257-405) antibodyTPH1 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 345-444) antibodyTPH1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (pSer58) antibodyTPH1 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 231-280) antibodyTPH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 26-75) antibodyTPH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (N-Term) antibodyTPH1 Reaktivität: Human, Maus, Ratte, Kaninchen, Huhn WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) antibodyTPH1 Reaktivität: Human WB, IHC, IF/ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (pSer58) antibodyTPH1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended Dilution: WB: 1:1000 IHC (frozen sections, Haycock et al., 2002): 1:1000 Quality Control: Western blots performed on each lot.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Lagerung
- -20 °C
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- Target
- Tryptophan Hydroxylase 1 (TPH1)
- Andere Bezeichnung
- TPH1 (TPH1 Produkte)
- Hintergrund
- Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin (Martinez et al., 2001). Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland (Haycock et al., 2002) . Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis (Martinez et al., 2001). Anti-Tryptophan Hydroxylase Western blot of human dorsal Raphe nucleus showing specifc immunolabeling of the ~55k tryptophan hydroxylase protein.
- Molekulargewicht
- '55 kDa
- Gen-ID
- 100101558
- UniProt
- P17290
- Pathways
- Feeding Behaviour
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