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Choline Acetyltransferase Antikörper

CHAT Reaktivität: Human WB, IHC Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN361419
  • Target Alle Choline Acetyltransferase (CHAT) Antikörper anzeigen
    Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
    Reaktivität
    • 70
    • 47
    • 42
    • 17
    • 5
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 66
    • 5
    • 4
    • 4
    • 3
    Ziege
    Klonalität
    • 70
    • 12
    Polyklonal
    Konjugat
    • 40
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Choline Acetyltransferase Antikörper ist unkonjugiert
    Applikation
    • 42
    • 22
    • 21
    • 20
    • 16
    • 14
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for the ~ 70k choline acetyltransferase protein
    Kreuzreaktivität
    Vogel, Huhn, Meerschweinchen, Human, Maus, Non-Human Primate
    Aufreinigung
    Affinity Purified
    Immunogen
    Native choline acetyltransferase purifed from human placenta
    Top Product
    Discover our top product CHAT Primärantikörper
  • Applikationshinweise
    Recommended Dilution: WB: 1:100 IHC: 1:100 Quality Control: Western blots performed on each lot.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    Lagerung
    -20 °C
  • Target
    Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
    Andere Bezeichnung
    CHAT (CHAT Produkte)
    Synonyme
    CHOACTASE antikoerper, CMS1A antikoerper, CMS1A2 antikoerper, ChoAcTase antikoerper, B230380D24Rik antikoerper, choline O-acetyltransferase antikoerper, choline O-acetyltransferase a antikoerper, choline acetyltransferase antikoerper, carnitine O-acetyltransferase antikoerper, CHAT antikoerper, chata antikoerper, Chat antikoerper, PGTG_00551 antikoerper, LOC100533322 antikoerper
    Hintergrund
    Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999). Anti-Choline Acetyltransferase Western blot of rat brain lysate showing specific immunolabeling of the ~70k ChAT
    Molekulargewicht
    '70 kDa
    Gen-ID
    1103
    Pathways
    Skeletal Muscle Fiber Development
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