DDC Antikörper

Produktnummer ABIN361424

Produktdetails anti-DDC Antikörper

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reaktivität: Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Specific for the ~55k DDC protein.

Kreuzreaktivität: Ratte (Rattus)

Homologie: Bovine

Aufreinigung: Antigen Affinity Purified from Pooled Serum

Immunogen: SDS denatured, recombinant bovine aromatic DOPA decarboxylase expressed in E. coli and purified from inclusion bodies

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Details zu DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Andere Bezeichnung: DDC (DDC Produkte)

Hintergrund: DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC, DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002, Berry et al., 1996, Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Anti-DOPA Decarboxylase Western blot of rat adrenal medulla. As shown in the autoradiograph, the antibody is specific for the ~55k DDC protein.

Molekulargewicht: '55 kDa

Gen-ID: 280762

UniProt: P27718

Pathways: Dopaminergic Neurogenesis