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SYT1 Antikörper (pSer309)

Name: SYT1 Antikörper (pSer309)
Brand: antibodies-online
SKU: ABIN361497
Price: 673.2 EUR
Availability: InStock

SYT1 Reaktivität: Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Western blots of rat cortex lysate showing specific immunolabeling of the ~60k - ~62k synaptotagmin phosphorylated at Ser309 (Control). (SYT1 Antikörper (pSer309))

Western blot of rat cortical lysate showing specific immunolabeling of the ~62 kDa synaptotagmin phosphorylated at Thr202 in the first lane (-). (SYT1 Antikörper (pSer309))

Immunostaining of 14 DIV rat cortical neurons showing synaptotagmin when phosphorylated at Thr202 in red and PSD95 in green. (SYT1 Antikörper (pSer309))

ISt

3 Abbildungen

(5 Referenzen)

Produktnummer ABIN361497

Datenblatt (PDF)

Target Alle SYT1 Antikörper anzeigen

SYT1 (Synaptotagmin I (SYT1))
Bindungsspezifität
15

12

8

8

5

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer309
Reaktivität
78

67

48

11

7

6

6

4

4

4

4

2

2

2

1

1

1

1
Ratte
Wirt
87

12

6

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
96

12
Polyklonal
Konjugat
63

8

6

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser SYT1 Antikörper ist unkonjugiert
Applikation
63

38

34

16

13

13

13

11

7

6

4

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität

Specific for the ~60k-62k synaptotagmin protein phosphorylated at Ser309.

Kreuzreaktivität

Ratte (Rattus)

Homologie

bovine, canine, chicken, human, mouse, non-human primate, zebra fish

Aufreinigung

Antigen Affinity Purified from Pooled Serum

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser309 conjugated to KLH

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SYT1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3A5 unconjugated

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SYT1 Reaktivität: Human, Ratte, Maus IHC, IF Wirt: Kaninchen Polyclonal unconjugated

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SYT1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1A6 unconjugated

anti-Synaptotagmin I (SYT1) (AA 301-523) antibody
SYT1 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Synaptotagmin I (SYT1) (pThr202) antibody
SYT1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Synaptotagmin I (SYT1) (AA 349-377), (C-Term) antibody
SYT1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33649 unconjugated

Applikationshinweise

Recommended Dilution: WB: 1:1000 IHC: 1:400 Quality Control: Western blots performed on each lot.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung

-20 °C
Leal-Ortiz, Waites, Terry-Lorenzo, Zamorano, Gundelfinger, Garner: "Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis." in: The Journal of cell biology, Vol. 181, Issue 5, pp. 831-46, (2008) (PubMed).

Poskanzer, Marek, Sweeney, Davis: "Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo." in: Nature, Vol. 426, Issue 6966, pp. 559-63, (2003) (PubMed).

Wang, Lu, Bai, Chang, Martin, Chapman, Jackson: "Different domains of synaptotagmin control the choice between kiss-and-run and full fusion." in: Nature, Vol. 424, Issue 6951, pp. 943-7, (2003) (PubMed).

Fernández-Chacón, Königstorfer, Gerber, García, Matos, Stevens, Brose, Rizo, Rosenmund, Südhof: "Synaptotagmin I functions as a calcium regulator of release probability." in: Nature, Vol. 410, Issue 6824, pp. 41-9, (2001) (PubMed).

Hilfiker, Pieribone, Nordstedt, Greengard, Czernik: "Regulation of synaptotagmin I phosphorylation by multiple protein kinases." in: Journal of neurochemistry, Vol. 73, Issue 3, pp. 921-32, (1999) (PubMed).
Target

SYT1 (Synaptotagmin I (SYT1))

Andere Bezeichnung

SYT1 (SYT1 Produkte)

Molekulargewicht

60/62 kDa

Gen-ID

25716

UniProt

P21707

Pathways

Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport