RPS6KA2 Antikörper (C-Term)

Produktnummer ABIN361520

Produktdetails anti-RPS6KA2 Antikörper

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Specific for the ~90k RSK2 protein.

Kreuzreaktivität: Human

Homologie: bovine, canine, chicken, mouse, rat

Aufreinigung: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Referenzen für anti-RPS6KA2 Antikörper (ABIN361520)

Hegde, Capell, Ibrahim, Klett, Patel, Sougiannis, Kelly: "Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 12, pp. 2920-2931, (2017) (PubMed).

Details zu RPS6KA2

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Andere Bezeichnung: RPS6KA2 (RPS6KA2 Produkte)

Synonyme: HU-2 antikoerper, MAPKAPK1C antikoerper, RSK antikoerper, RSK3 antikoerper, S6K-alpha antikoerper, S6K-alpha2 antikoerper, p90-RSK3 antikoerper, pp90RSK3 antikoerper, 90kDa antikoerper, D17Wsu134e antikoerper, Rps6ka-rs1 antikoerper, Rsk3 antikoerper, p90rsk antikoerper, pp90rsk antikoerper, ribosomal protein S6 kinase A2 antikoerper, ribosomal protein S6 kinase, polypeptide 2 antikoerper, Rps6ka2 antikoerper, RPS6KA2 antikoerper

Hintergrund: The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006). Anti-Ribosomal S6 Kinase Western blot of rat hippocampal lysate showing specific immunolabeling of the ~90k RSK2 protein.

Molekulargewicht: '90 kDa

Gen-ID: 20112

UniProt: Q9WUT3

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades