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c-MET Antikörper (pTyr1349)

MET Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN362291

Datenblatt (PDF)

Target Alle c-MET (MET) Antikörper anzeigen

c-MET (MET) (Met Proto-Oncogene (MET))
Bindungsspezifität
42

28

28

28

12

11

9

7

7

7

6

5

4

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr1349
Reaktivität
233

134

102

6

6

5

4

4

2

2

2

1

1

1

1
Human, Maus, Ratte
Wirt
204

39

3

2
Kaninchen
Passende Sekundärantikörper
Klonalität
197

51
Polyklonal
Konjugat
131

19

11

11

7

7

7

7

7

7

6

6

2

2

2

2

2

2

2

2

2

2

2
Dieser c-MET Antikörper ist unkonjugiert
Applikation
164

105

44

31

27

21

15

14

13

9

8

5

4

4

1

1

1
Western Blotting (WB)

Spezifität

The antibody detects endogenous level of Met only when phosphorylated at tyrosine 1349.

Aufreinigung

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen

Peptide sequence around phosphorylation site of pTyr1349 (E-H-Y (p) -V-H) derived from Human Met. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotyp

IgG

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Applikationshinweise

Western blotting: 1:500-1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

c-MET (MET) (Met Proto-Oncogene (MET))

Andere Bezeichnung

Met (MET Produkte)

Hintergrund

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Molekulargewicht

156 kDa

NCBI Accession

NP_000236

UniProt

P08581

Pathways

RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor