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RPS6KB1 Antikörper (pThr421)
RPS6KB1
Reaktivität: Human, Maus, Ratte
WB, IHC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-RPS6KB1 Antikörper
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Target
Alle RPS6KB1 Antikörper anzeigen
RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Bindungsspezifität
Alle Epitope für RPS6KB1 Antikörper
pThr421
Reaktivität
Alle Reaktivitäten für RPS6KB1 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für RPS6KB1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für RPS6KB1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für RPS6KB1 Antikörper
Dieser RPS6KB1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für RPS6KB1 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Spezifität
The antibody detects endogenous level of p70 S6 Kinase only when phosphorylated at threonine 421.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
Peptide sequence around phosphorylation site of pThr421 (P-R-T (p) -P-V) derived from Human p70 S6 Kinase. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotyp
IgG
Top Product
Discover our top product RPS6KB1 Primärantikörper
Alternativen
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anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pThr389), (pThr412) antibody
RPS6KB1
Reaktivität: Human, Maus, Ratte, Schwein
WB, IHC, ELISA, IF, ICC
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Referenzen für anti-RPS6KB1 Antikörper (ABIN362316)
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Tang, Zhou, Zhou : "Dauricine inhibits insulin-like growth factor-I-induced hypoxia inducible factor 1alpha protein accumulation and vascular endothelial growth factor expression in human breast cancer cells. " in: Acta pharmacologica Sinica , Vol. 30 , Issue 5 , pp. 605-16 , (2009 ) (PubMed ).
Details zu RPS6KB1
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Target
RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Andere Bezeichnung
p70 S6 Kinase (RPS6KB1 Produkte )
Synonyme
PS6K antikoerper, S6K antikoerper, S6K-beta-1 antikoerper, S6K1 antikoerper, STK14A antikoerper, p70 S6KA antikoerper, p70(S6K)-alpha antikoerper, p70-S6K antikoerper, p70-alpha antikoerper, 10539 antikoerper, 7084 antikoerper, CG10539 antikoerper, DS6K antikoerper, Dmel\\CG10539 antikoerper, Dp70S6k antikoerper, Dp70[s6k] antikoerper, Dp70s6k antikoerper, S6k antikoerper, dS6K antikoerper, dS6k antikoerper, dp70[S6k] antikoerper, dp70s6k antikoerper, dps6k antikoerper, ds6k antikoerper, fs(3)07084 antikoerper, l(3)07084 antikoerper, p70 S6K antikoerper, p70/S6K antikoerper, p70S6K antikoerper, p70[S6 kinase] antikoerper, p70[S6K] antikoerper, p70[S6k] antikoerper, p70[S6kinase] antikoerper, p70s6K antikoerper, s6k antikoerper, s6k11 antikoerper, 2610318I15Rik antikoerper, 4732464A07Rik antikoerper, 70kDa antikoerper, AA959758 antikoerper, AI256796 antikoerper, AI314060 antikoerper, p70/85s6k antikoerper, p70s6k antikoerper, p70s6k-A antikoerper, p70-s6k antikoerper, ps6k antikoerper, rps6kb1 antikoerper, rps6kb1-A antikoerper, s6K1 antikoerper, stk14a antikoerper, fc51h01 antikoerper, wu:fc51h01 antikoerper, zgc:55713 antikoerper, ribosomal protein S6 kinase B1 antikoerper, Ribosomal protein S6 kinase antikoerper, ribosomal protein S6 kinase, polypeptide 1 antikoerper, ribosomal protein S6 kinase B1 L homeolog antikoerper, ribosomal protein S6 kinase B1 S homeolog antikoerper, ribosomal protein S6 kinase b, polypeptide 1b antikoerper, RPS6KB1 antikoerper, S6k antikoerper, Rps6kb1 antikoerper, rps6kb1.L antikoerper, rps6kb1.S antikoerper, rps6kb1b antikoerper
Hintergrund
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.
Molekulargewicht
85 kDa
NCBI Accession
NP_003152
UniProt
P23443
Pathways
PI3K-Akt Signalweg , RTK Signalweg , AMPK Signaling , Regulation of Cell Size , Skeletal Muscle Fiber Development , Feeding Behaviour , G-protein mediated Events , Smooth Muscle Cell Migration , Interaction of EGFR with phospholipase C-gamma , Warburg Effekt
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