EIF2A Antikörper (pSer51)
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- Target Alle EIF2A Antikörper anzeigen
- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
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Bindungsspezifität
- pSer51
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EIF2A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Spezifität
- The antibody detects endogenous level of eIF2a only when phosphorylated at serine 51.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogen
- Peptide sequence around phosphorylation site of pSer51 (E-L-S (p) -R-R) derived from Human eIF2a. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Isotyp
- IgG
- Top Product
- Discover our top product EIF2A Primärantikörper
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- Applikationshinweise
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
- Andere Bezeichnung
- eIF2alpha (EIF2A Produkte)
- Synonyme
- ATEIF2-A2 antikoerper, EIF2-A2 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, EIF-2A antikoerper, MST089 antikoerper, MSTP004 antikoerper, MSTP089 antikoerper, D030048D22 antikoerper, D3Ertd194e antikoerper, im:7145971 antikoerper, zgc:110460 antikoerper, DDBDRAFT_0185936 antikoerper, DDBDRAFT_0234177 antikoerper, DDB_0185936 antikoerper, DDB_0234177 antikoerper, Eif2a antikoerper, eif2a antikoerper, eif2alpha antikoerper, EIF2A antikoerper, CG9946 antikoerper, Dmel\\CG9946 antikoerper, Eif2alpha antikoerper, IF2A_DROME antikoerper, M(1)14C antikoerper, M(1)19-153 antikoerper, M(1)8e3-10 antikoerper, deIF2alpha antikoerper, eIF-2 antikoerper, eIF-2 a antikoerper, eIF-2 alpha antikoerper, eIF2 alpha antikoerper, eIF2-alpha antikoerper, eIF2a antikoerper, eIF2alpha antikoerper, eiF-2alpha antikoerper, elF2alpha antikoerper, l(1)14Cf antikoerper, l(1)19-153 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, eukaryotic translation initiation factor 2A antikoerper, eukaryotic translation initiation factor 2A, 65kDa antikoerper, eukaryotic translation initiation factor 2A S homeolog antikoerper, eukaryotic translation initiation factor antikoerper, eukaryotic translation Initiation Factor 2alpha antikoerper, EIF2 ALPHA antikoerper, EIF2A antikoerper, Eif2a antikoerper, eif2a antikoerper, eIF2a antikoerper, eif2a.S antikoerper, eif2A antikoerper, eIF-2alpha antikoerper
- Hintergrund
- Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
- Molekulargewicht
- 38 kDa
- NCBI Accession
- NP_004085
- UniProt
- P05198
- Pathways
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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