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NFKB1 Antikörper (AA 335-339)
NFKB1
Reaktivität: Human, Maus, Ratte
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-NFKB1 Antikörper
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Target
Alle NFKB1 Antikörper anzeigen
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Bindungsspezifität
Alle Epitope für NFKB1 Antikörper
AA 335-339
Reaktivität
Alle Reaktivitäten für NFKB1 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für NFKB1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für NFKB1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für NFKB1 Antikörper
Dieser NFKB1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für NFKB1 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Spezifität
The antibody detects endogenous level of total NFkB-p105/p50 protein.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 335-339 (R-K-S-D-L) derived from Human NFkB-p105. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Details zu NFKB1
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Target
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Andere Bezeichnung
NFkappaB-p105/p50 (NFKB1 Produkte )
Synonyme
GKLP antikoerper, NKTL antikoerper, NTKL antikoerper, P105 antikoerper, TAPK antikoerper, TEIF antikoerper, TRAP antikoerper, EBP-1 antikoerper, KBF1 antikoerper, NF-kB1 antikoerper, NF-kappa-B antikoerper, NF-kappaB antikoerper, NFKB-p105 antikoerper, NFKB-p50 antikoerper, NFkappaB antikoerper, p105 antikoerper, p50 antikoerper, NF-kB antikoerper, NF-KB1 antikoerper, ebp-1 antikoerper, kbf1 antikoerper, nf-kappa-b antikoerper, nf-kappaB antikoerper, nfkb-p105 antikoerper, nfkb-p50 antikoerper, NF-kappaB1 antikoerper, p50/p105 antikoerper, BICDR-1 antikoerper, bicdr1 antikoerper, ccdc64 antikoerper, SCY1 like pseudokinase 1 antikoerper, nuclear factor kappa B subunit 1 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antikoerper, nuclear factor NF-kappa-B p105 subunit antikoerper, nucleoporin 107 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antikoerper, SCYL1 antikoerper, NFKB1 antikoerper, Nfkb1 antikoerper, nfkb1.L antikoerper, CpipJ_CPIJ012236 antikoerper, Nup107 antikoerper, nfkb1 antikoerper
Hintergrund
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
Molekulargewicht
120 kDa
NCBI Accession
NP_001158
UniProt
P19838
Pathways
p53 Signalweg , NF-kappaB Signalweg , RTK Signalweg , T-Zell Rezeptor Signalweg , TLR Signalweg , Fc-epsilon Rezeptor Signalübertragung , Neurotrophin Signalübertragung , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , S100 Proteine
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