×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
STAT3 Antikörper (AA 725-729)
STAT3
Reaktivität: Human, Maus, Ratte
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-STAT3 Antikörper
(ausblenden)
Target
Alle STAT3 Antikörper anzeigen
STAT3
(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
Bindungsspezifität
Alle Epitope für STAT3 Antikörper
AA 725-729
Reaktivität
Alle Reaktivitäten für STAT3 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für STAT3 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für STAT3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für STAT3 Antikörper
Dieser STAT3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für STAT3 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Spezifität
The antibody detects endogenous level of total STAT3 protein.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 725-729 (P-M-S-P-R) derived from Human STAT3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotyp
IgG
Top Product
Discover our top product STAT3 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Referenzen für anti-STAT3 Antikörper (ABIN362567)
(ausblenden)
Cheng, Wang, Xia, Yan, Tang, Chen, Zhang, Liu, Kong, Sjöberg, Folco, Libby, Liao, Shi : "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation. " in: EMBO molecular medicine , Vol. 4 , Issue 10 , pp. 1112-25 , (2012 ) (PubMed ).
Yu, Qin, He, Wang, Fu, Liu, Guo, Liang, Dou, Han : "Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling. " in: Hepatology (Baltimore, Md.) , Vol. 54 , Issue 3 , pp. 979-88 , (2011 ) (PubMed ).
Details zu STAT3
(ausblenden)
Target
STAT3
(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
Andere Bezeichnung
STAT3 (STAT3 Produkte )
Synonyme
1110034C02Rik antikoerper, AW109958 antikoerper, Aprf antikoerper, APRF antikoerper, HIES antikoerper, Xstat3 antikoerper, aprf antikoerper, hies antikoerper, stat3 antikoerper, wu:fc15d02 antikoerper, wu:fl59g06 antikoerper, z-Stat3 antikoerper, signal transducer and activator of transcription 3 antikoerper, signal transduction and activation of transcription 3 antikoerper, signal transducer and activator of transcription 3, gene 1 L homeolog antikoerper, signal transducer and activator of transcription 3 (acute-phase response factor) antikoerper, STAT3 antikoerper, stat3 antikoerper, Stat3 antikoerper, stat3.1.L antikoerper
Hintergrund
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.
Molekulargewicht
88 kDa
NCBI Accession
NP_003141
UniProt
P40763
Pathways
JAK-STAT Signalweg , RTK Signalweg , Interferon-gamma Pathway , Neurotrophin Signalübertragung , Dopaminergic Neurogenesis , Response to Growth Hormone Stimulus , Carbohydrate Homeostasis , Stem Cell Maintenance , Hepatitis C , Protein targeting to Nucleus , Feeding Behaviour , CXCR4-mediated Signaling Events , Signaling of Hepatocyte Growth Factor Receptor
Zuletzt angesehen
(ausblenden)