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HDAC4/HDAC5/HDAC9 Antikörper (AA 244-248)

Reaktivität: Human, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN363088
  • Target Alle HDAC4/HDAC5/HDAC9 Produkte
    HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)
    Bindungsspezifität
    • 10
    • 10
    • 9
    • 2
    • 1
    • 1
    AA 244-248
    Reaktivität
    • 20
    • 10
    • 1
    Human, Maus
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser HDAC4/HDAC5/HDAC9 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Spezifität
    The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody detects endogenous levels of total HDAC4/HDAC5/HDAC9 protein.
    Immunogen
    Peptide sequence around AA 244-248, 257-261, 218-222 (T-A-S-E-P) derived from Human HDAC4, HDAC5, HDAC9. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotyp
    IgG
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)
    Andere Bezeichnung
    HDAC4/HDAC5/HDAC9 (HDAC4/HDAC5/HDAC9 Produkte)
    Synonyme
    AHO3 antikoerper, BDMR antikoerper, HA6116 antikoerper, HD4 antikoerper, HDAC-4 antikoerper, HDAC-A antikoerper, HDACA antikoerper, histone deacetylase 4 antikoerper, HDAC4 antikoerper
    Hintergrund
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
    Molekulargewicht
    124 kDa
    NCBI Accession
    NP_055522, NP_001015
    UniProt
    Q9UKV0
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