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ARNT Antikörper (AA 496-789)

ARNT Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Schwein, Affe, Frettchen WB, IHC, IP, IHC (p), ChIP, GS Wirt: Maus Monoclonal H1beta234 unconjugated
Produktnummer ABIN363204
  • Target Alle ARNT Antikörper anzeigen
    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
    Bindungsspezifität
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 496-789
    Reaktivität
    • 59
    • 21
    • 20
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Schaf, Schwein, Affe, Frettchen
    Wirt
    • 46
    • 13
    • 3
    Maus
    Klonalität
    • 38
    • 24
    Monoklonal
    Konjugat
    • 48
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ARNT Antikörper ist unkonjugiert
    Applikation
    • 44
    • 15
    • 13
    • 13
    • 11
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS)
    Spezifität
    Reacts with human HIF 1 beta /ARNT
    Kreuzreaktivität
    Maus, Rind (Kuh), Schaf, Ratte (Rattus)
    Kreuzreaktivität (Details)
    Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.
    Aufreinigung
    Purified (protein G)
    Immunogen
    Fusion protein containing amino acids 496-789 of human HIF-1 beta
    Klon
    H1beta234
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product ARNT Primärantikörper
  • Applikationshinweise

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    ChIP1:10-1:500, IHC1:100, IHC-P 1:100, WB 1:500

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.4 mg/mL
    Buffer
    PBS, Sodium azide 0.05 %
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
  • Target
    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
    Andere Bezeichnung
    Hypoxia-Inducible Factor 1-beta (ARNT Produkte)
    Hintergrund
    HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits which are bHLH proteins of PAS (PER, ARNT, SIM) family. HIF-1 beta forms heterodimer with AHR, AHRR, HIF1 alpha and EPAS1/HIF2 alpha as well as with other bHLH proteins and its dimerization is required for efficient DNA binding. Interact with TACC3 and NOCA7.
    Gen-ID
    405
    UniProt
    P27540
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt
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