PRDM1 Antikörper (AA 199-409)

Produktnummer ABIN363225

Produktdetails anti-PRDM1 Antikörper

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Bindungsspezifität: AA 199-409

Reaktivität: Human, Maus, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRDM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Spezifität: Reacts with ~98 kDa BLIMP-1 from mouse, pig and human

Kreuzreaktivität (Details): May cross reacts with the beta form (~80 kDa).

Aufreinigung: Purified (protein G)

Immunogen: A fragment of the mouse Blimp-1 (residues 199-409)

Klon: 3H2-E8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ELISA: 1/100 to 1/2000 - ICC/ IF: 1/50 to 1/100 - IHC: 1/200 -FC: 8 μg/mL (for 2 x 10E6 cells/mL) - WB: 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: , Sodium azide 0.1 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 6 months

Details zu PRDM1

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Andere Bezeichnung: B Lymphocyte-Induced Maturation Protein-1 (BLIMP-1) (PRDM1 Produkte)

Hintergrund: Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus.It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages.Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells.Blimp-1 has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.

Gen-ID: 639

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation