APEX1 Antikörper
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- Target Alle APEX1 Antikörper anzeigen
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
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Reaktivität
- Human, Maus, Ratte, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser APEX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Neutralization (Neut)
- Spezifität
- Reacts with human ~37 kDa APE-1 protein
- Kreuzreaktivität
- Maus, Kaninchen, Ratte (Rattus)
- Kreuzreaktivität (Details)
- Cross reacts with proteins from mouse, rat and rabbit.
- Aufreinigung
- Antigen affinity purified
- Immunogen
- Affinity purified human Apurinic/Apyrimidinic Endonuclease (APE/ref-1) fusion protein
- Top Product
- Discover our top product APEX1 Primärantikörper
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anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibody
APEX1 Reaktivität: Human WB, IF, IHC (p) Wirt: Maus Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 219-318) antibodyAPEX1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 7A2G7 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-242) antibodyAPEX1 Reaktivität: Human, Hund, Affe WB, IHC, IHC (p) Wirt: Maus Monoclonal 1H9 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 2-318) antibodyAPEX1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (acLys6) antibodyAPEX1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) antibodyAPEX1 Reaktivität: Human WB, IF, IHC (p) Wirt: Maus Monoclonal 1518CT337-123-86-269-232 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (N-Term) antibodyAPEX1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC: 1/1 000 - WB : 1/1 000 - B/N: 50-200 Molar excess - ChIP: 1/10-1/500 - ICC/IF: 1/50-1/200 - IP: 7 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Tris-glycine, NaCl 150 mM buffer, Sodium azide 0.05 %
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C/-80 °C
- Informationen zur Lagerung
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- Target
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Andere Bezeichnung
- DNA-(Apurinic Or Apyrimidinic Site) Lyase (APE-1) (APEX1 Produkte)
- Hintergrund
- Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents.
- Gen-ID
- 328
- Pathways
- DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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