HMGA1 Antikörper (AA 12-23)

Produktnummer ABIN364402

Produktdetails anti-HMGA1 Antikörper

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Bindungsspezifität: AA 12-23

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Pferd, Fledermaus, Hamster, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser HMGA1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human HMGA1. This antibody is expected to recognise isoform a (also called HMG-I, NP_665906.1, NP_665908.1) and isoform b (also called HMG-Y, NP_002122.1, NP_665909.1, NP_665910.1, NP_665912.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Dog, Horse, Rabbit, Pig (100%) Gibbon, Bovine, Opossum (92%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-LASKQEKDGTEK from an internal region of human HMGA1 (NP_665906.1, NP_665908.1, NP_002122.1, NP_665909.1, NP_665912.1, NP_665910.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Dog, Horse, Rabbit, Pig (100%), Gibbon, Bovine, Opossum (92%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (4 μg/mL), Peptide-ELISA (1:32000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 4 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Andere Bezeichnung: HMGIY / HMGA1 (HMGA1 Produkte)

Synonyme: HMG-R antikoerper, HMGA1A antikoerper, HMGIY antikoerper, Hmgi antikoerper, Hmgiy antikoerper, hmga1 antikoerper, hmgiy antikoerper, wu:fb12b06 antikoerper, wu:fb18f11 antikoerper, wu:fc19f01 antikoerper, wu:fi38b05 antikoerper, zgc:85677 antikoerper, AL023995 antikoerper, Hmga1a antikoerper, Hmga1b antikoerper, Hmgy antikoerper, HMG-I(Y) antikoerper, HMG-Y antikoerper, HMGA1 antikoerper, zgc:153948 antikoerper, high mobility group AT-hook 1 antikoerper, high mobility group protein HMG-I/HMG-Y antikoerper, high mobility group AT-hook 1a antikoerper, high mobility group AT-hook 1b antikoerper, HMGA1 antikoerper, Hmga1 antikoerper, TSC_c24220 antikoerper, hmga1a antikoerper, LOC705105 antikoerper, hmga1b antikoerper

Hintergrund: Name/Gene ID: HMGA1

Synonyms: HMGA1, High mobility group protein A1, High mobility group protein R, HMG-R, Hmg-i, HMGIY, High mobility group AT-hook 1, HMG-I(Y), HMGA1A

Gen-ID: 3159

NCBI Accession: NP_665906, NP_665908, NP_002122, NP_665909, NP_665912, NP_665910

Pathways: Nuclear Hormone Receptor Binding, Autophagie