CD45 Antikörper (FITC)
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- Target Alle CD45 (PTPRC) Antikörper anzeigen
- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD45 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- CD45RB
- Produktmerkmale
- Synonyms: Leukocyte common antigen, L-CA, PTPRC, T200, CD45RB, CD45RO, CD45RA, CD45R
- Immunogen
- Cloned mouse Th2 cell lines. (Ref. 1)
- Klon
- C363-16A
- Isotyp
- IgG2a
- Top Product
- Discover our top product PTPRC Primärantikörper
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- Applikationshinweise
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Flow Cytometry. < / = 1 μg/10^6 cells. (Ref.1-3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Fluorescein Isothiocyanate Isomer 1 (FITC)
- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
- Andere Bezeichnung
- CD45 / LCA (PTPRC Produkte)
- Synonyme
- PTPRC antikoerper, si:dkeyp-47c5.1 antikoerper, B220 antikoerper, CD45 antikoerper, CD45R antikoerper, GP180 antikoerper, L-CA antikoerper, LCA antikoerper, LY5 antikoerper, T200 antikoerper, Cd45 antikoerper, Ly-5 antikoerper, Lyt-4 antikoerper, loc antikoerper, Lca antikoerper, RT7 antikoerper, cd45 antikoerper, protein tyrosine phosphatase, receptor type C antikoerper, protein tyrosine phosphatase, receptor type, C antikoerper, receptor-type tyrosine-protein phosphatase C antikoerper, PTPRC antikoerper, ptprc antikoerper, LOC100074271 antikoerper, Ptprc antikoerper
- Hintergrund
- CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naive T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naive to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4 T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1. Distribution: Peripheral B cells, naive T cells, most thymocytes, low density on macrophages and dendritic cells. Function: Phosphatase, T cell development and activation Structure: Phosphatase receptor (CD45 gene exon 5), 220 kDSynonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
- UniProt
- P06800
- Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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