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Retinoic Acid Receptor alpha Antikörper (N-Term)
RARA
Reaktivität: Human, Maus, Rind (Kuh), Hund
WB
Wirt: Maus
Monoclonal
763
unconjugated
Produktdetails anti-Retinoic Acid Receptor alpha Antikörper
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Target
Alle Retinoic Acid Receptor alpha (RARA) Antikörper anzeigen
Retinoic Acid Receptor alpha (RARA)
(Retinoic Acid Receptor, alpha (RARA))
Bindungsspezifität
Alle Epitope für Retinoic Acid Receptor alpha Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für Retinoic Acid Receptor alpha Antikörper
Human, Maus, Rind (Kuh), Hund
Wirt
Alle Wirte für Retinoic Acid Receptor alpha Antikörper
Maus
Klonalität
Alle Klonalitäten für Retinoic Acid Receptor alpha Antikörper
Monoklonal
Konjugat
Alle Konjugate für Retinoic Acid Receptor alpha Antikörper
Dieser Retinoic Acid Receptor alpha Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Retinoic Acid Receptor alpha Antikörper
Western Blotting (WB)
Spezifität
This antibody is specific for the ~48k RAR-alpha isotype.
Kreuzreaktivität (Details)
Species reactivity (expected):Bovine, Canine (Dog) and Mouse. Species reactivity (tested):Human.
Produktmerkmale
Synonyms: NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1
Aufreinigung
Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.
Immunogen
Peptide corresponding to amino acid residues from the N-terminal region of humanretinoic acid receptor, alpha-isotype.
Klon
763
Isotyp
IgG1
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Details zu Retinoic Acid Receptor alpha
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Target
Retinoic Acid Receptor alpha (RARA)
(Retinoic Acid Receptor, alpha (RARA))
Andere Bezeichnung
RAR-alpha / RARA (RARA Produkte )
Synonyme
NR1B1 antikoerper, RAR antikoerper, Nr1b1 antikoerper, RARalpha1 antikoerper, rar-alpha antikoerper, etID309833.12 antikoerper, rara antikoerper, rara2a antikoerper, zRAR antikoerper, zRAR-alpha antikoerper, zgc:109797 antikoerper, nr1b1 antikoerper, RAR-ALPHA1 antikoerper, HS-RARa antikoerper, fj66e06 antikoerper, rara2b antikoerper, wu:fj66e06 antikoerper, retinoic acid receptor alpha antikoerper, retinoic acid receptor, alpha antikoerper, retinoic acid receptor, alpha a antikoerper, retinoic acid receptor alpha L homeolog antikoerper, retinoic acid receptor, alpha b antikoerper, RARA antikoerper, Rara antikoerper, LOC100136372 antikoerper, raraa antikoerper, rara.L antikoerper, rara antikoerper, rarab antikoerper
Hintergrund
Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: NR1B1, Nuclear receptor subfamily 1 group B member 1, Retinoic acid receptor alpha
Gen-ID
5914
UniProt
P10276
Pathways
Nuclear Receptor Transcription Pathway , Retinoic Acid Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Steroid Hormone Mediated Signaling Pathway , Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , S100 Proteine
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