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THRA Antikörper (N-Term)
THRA
Reaktivität: Human, Maus, Ratte, Hund
WB
Wirt: Maus
Monoclonal
2103
unconjugated
Produktdetails anti-THRA Antikörper
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Target
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THRA
(Thyroid Hormone Receptor, alpha (THRA))
Bindungsspezifität
Alle Epitope für THRA Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für THRA Antikörper
Human, Maus, Ratte, Hund
Wirt
Alle Wirte für THRA Antikörper
Maus
Klonalität
Alle Klonalitäten für THRA Antikörper
Monoklonal
Konjugat
Alle Konjugate für THRA Antikörper
Dieser THRA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für THRA Antikörper
Western Blotting (WB)
Spezifität
AM08268PU-N is specific for the ~50k THR alpha-1 and the ~58k THR alpha-2 proteins.
Kreuzreaktivität (Details)
Species reactivity (expected):Canine (Dog), Mouse and Rat. Species reactivity (tested):Human.
Produktmerkmale
Synonyms: Thyroid hormone receptor alpha, THRA1, THRA2, C-erbA-alpha, c-erbA-1, EAR-7, EAR7,NR1A1, Nuclear receptor subfamily 1 group A member 1
Aufreinigung
Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.
Immunogen
Peptide corresponding to amino acid residues from the N-terminal region of human thyroidhormone receptor, alpha1/alpha2-isotype.
Klon
2103
Isotyp
IgG1
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Details zu THRA
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Target
THRA
(Thyroid Hormone Receptor, alpha (THRA))
Andere Bezeichnung
THRA / ERBA1 (THRA Produkte )
Synonyme
AR7 antikoerper, CHNG6 antikoerper, EAR7 antikoerper, ERB-T-1 antikoerper, ERBA antikoerper, ERBA1 antikoerper, NR1A1 antikoerper, THRA1 antikoerper, THRA2 antikoerper, c-ERBA-1 antikoerper, C-ERBA-ALPHA antikoerper, TRalpha antikoerper, c-erba antikoerper, erba antikoerper, nr1a1-A antikoerper, thra-A antikoerper, thra1 antikoerper, TR[a]1 antikoerper, nr1a1 antikoerper, thra antikoerper, thral antikoerper, tra antikoerper, tra1 antikoerper, wu:fb59g07 antikoerper, Thra1 antikoerper, 6430529J03Rik antikoerper, AW259572 antikoerper, Erba antikoerper, Nr1a1 antikoerper, Rvr antikoerper, T3R[a] antikoerper, T3Ralpha antikoerper, Thra2 antikoerper, C-ERBA ALPHA1 antikoerper, Thra antikoerper, fTHRalphaA antikoerper, nr1a1-a antikoerper, thyroid hormone receptor, alpha antikoerper, thyroid hormone receptor, alpha L homeolog antikoerper, thyroid hormone receptor alpha a antikoerper, thyroid hormone receptor alpha antikoerper, thyroid hormone receptor alpha-A antikoerper, THRA antikoerper, thra.L antikoerper, thraa antikoerper, Thra antikoerper, tr-alpha antikoerper, LOC109641414 antikoerper
Hintergrund
Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TR-alpha1, TR-alpha2, TR-beta1 and TR-beta2. TR-alpha1, TR-beta1 and TR-beta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).Synonyms: C-erbA-alpha, EAR-7, EAR7, NR1A1, Nuclear receptor subfamily 1 group A member 1, THRA1, THRA2, Thyroid hormone receptor alpha, c-erbA-1
Gen-ID
7067
UniProt
P10827
Pathways
Nuclear Receptor Transcription Pathway , Steroid Hormone Mediated Signaling Pathway , Sensory Perception of Sound , Cellular Response to Molecule of Bacterial Origin , Regulation of Lipid Metabolism by PPARalpha , Regulation of Muscle Cell Differentiation , Maintenance of Protein Location , Skeletal Muscle Fiber Development
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