SLC6A1 Antikörper (C-Term)
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- Target Alle SLC6A1 (GAT1) Antikörper anzeigen
- SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC6A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Specific for the ~67k GAT-1 protein. Immunolabeling is blocked by the peptide used as antigen.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Rat. - Aufreinigung
- Affinity Chromatography.
- Immunogen
- Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.
- Isotyp
- IgG
- Top Product
- Discover our top product GAT1 Primärantikörper
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- Applikationshinweise
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Western Blot: 1/1000. Immunohistochemitsry: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Target
- SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))
- Andere Bezeichnung
- GAT1 / SLC6A1 (GAT1 Produkte)
- Synonyme
- GABATHG antikoerper, GABATR antikoerper, GAT1 antikoerper, A730043E01 antikoerper, GAT-1 antikoerper, Gabt antikoerper, Gabt1 antikoerper, Gat1 antikoerper, XT-1 antikoerper, Xtrp1 antikoerper, si:ch211-280e18.1 antikoerper, si:dkey-164m14.1 antikoerper, slc6a1 antikoerper, solute carrier family 6 member 1 antikoerper, solute carrier family 6 (neurotransmitter transporter, GABA), member 1 antikoerper, solute carrier family 6 (neurotransmitter transporter, GABA), member 1, like antikoerper, GABA neurotransmitter transporter 1 antikoerper, SLC6A1 antikoerper, Slc6a1 antikoerper, slc6a1l antikoerper, slc6a1 antikoerper
- Hintergrund
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).Synonyms: GABA transporter 1, GABATR, GABT1, GAT-1, Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1
- Gen-ID
- 79212
- NCBI Accession
- NP_077347
- UniProt
- P23978
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