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TAO Kinase 2 Antikörper (pSer181)
TAOK2
Reaktivität: Human, Maus, Ratte, Hund, Xenopus laevis, Fink, Zebrafisch (Danio rerio)
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-TAO Kinase 2 Antikörper
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Target
Alle TAO Kinase 2 (TAOK2) Antikörper anzeigen
TAO Kinase 2 (TAOK2)
Bindungsspezifität
Alle Epitope für TAO Kinase 2 Antikörper
pSer181
Reaktivität
Human, Maus, Ratte, Hund, Xenopus laevis, Fink, Zebrafisch (Danio rerio)
Wirt
Alle Wirte für TAO Kinase 2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TAO Kinase 2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für TAO Kinase 2 Antikörper
Dieser TAO Kinase 2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TAO Kinase 2 Antikörper
Western Blotting (WB)
Spezifität
Specific for the ~120k TAO2 phosphorylated at Ser181 in Western blots. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.
Kreuzreaktivität (Details)
Species reactivity (expected):Canine, Finch, Xenopus and Zebrafish. Species reactivity (tested):Human, Mouse and Rat.
Aufreinigung
Affinity Chromatography via sequential chromatography on phospho- and dephosphopeptide affinity columns.
Immunogen
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser181 of TAO2.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody undiluted (in aliquots) at-20 °C.
Details zu TAO Kinase 2
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Target
TAO Kinase 2 (TAOK2)
Abstract
TAOK2 Produkte
Synonyme
MAP3K17 antikoerper, PSK antikoerper, PSK1 antikoerper, PSK1-BETA antikoerper, TAO1 antikoerper, TAO2 antikoerper, Tao2 antikoerper, 1110033K02Rik antikoerper, B230344N16 antikoerper, mKIAA0881 antikoerper, TAOK2 antikoerper, map3k17 antikoerper, psk antikoerper, psk1 antikoerper, tao1 antikoerper, tao2 antikoerper, TAO kinase 2 antikoerper, TAO kinase 2 L homeolog antikoerper, serine/threonine-protein kinase TAO2 antikoerper, TAOK2 antikoerper, Taok2 antikoerper, taok2.L antikoerper, taok2 antikoerper, LOC100085396 antikoerper
Hintergrund
In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999, Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.Synonyms: KFC-C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK-1, PSK1, Prostate-derived STE20-like kinase 1, Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, UNQ2971/PRO7431
Gen-ID
9344
NCBI Accession
NP_004774
UniProt
Q9UL54
Pathways
Cell-Cell Junction Organization
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