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Vimentin Antikörper

Name: Vimentin Antikörper
SKU: ABIN372741
Price: 765.69 EUR
Availability: InStock

VIM Reaktivität: Human, Maus, Ratte, Säugetier WB, IF, IHC (fro) Wirt: Huhn Polyclonal unconjugated

Image no. 2 for anti-Vimentin (VIM) antibody (ABIN372741) (Vimentin Antikörper)

Image no. 1 for anti-Vimentin (VIM) antibody (ABIN372741) (Vimentin Antikörper)

2 Abbildungen

(3 Referenzen)

Produktnummer ABIN372741

Datenblatt (PDF)

Target Alle Vimentin (VIM) Antikörper anzeigen

Vimentin (VIM)
Reaktivität
305

120

117

61

60

50

43

38

30

22

20

14

13

8

8

6

5

3

3

2

1

1

1

1

1

1

1

1

1
Human, Maus, Ratte, Säugetier
Wirt
158

131

10

6

6

5

2
Huhn
Klonalität
171

146
Polyklonal
Konjugat
198

15

13

12

9

7

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1
Dieser Vimentin Antikörper ist unkonjugiert
Applikation
263

115

105

97

88

64

48

40

39

32

23

20

8

5

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität

Specific for the ~50 kDa Vimentin protein.

Kreuzreaktivität (Details)

Species reactivity (expected):other Mammalian.
Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung

Ig Fraction

Immunogen

Recombinant human Vimentin purified from E. coli.

Isotyp

Ig Fraction

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anti-Vimentin (VIM) (AA 371-466) antibody
VIM Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Affe WB, ELISA, FACS, IHC (p), ICC, IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) antibody
KO Validated VIM Reaktivität: Human WB, IHC, ELISA, IF, IHC (p), ICC, IP, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Säugetier WB, FACS, IHC (p), ICC Wirt: Maus Monoclonal VI-01 unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human, Maus, Ratte, Schwein, Huhn WB, IHC (p), ICC, IP Wirt: Maus Monoclonal VI-10 unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human, Maus WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB41034 unconjugated

anti-Vimentin (VIM) (AA 1-200) antibody
VIM Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human WB, IHC, ICC, IP Wirt: Maus Monoclonal C8 unconjugated

anti-Vimentin (VIM) (AA 430-457), (C-Term) antibody
VIM Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB16691 unconjugated

anti-Vimentin (VIM) (AA 41-140) antibody
VIM Reaktivität: Human WB, ELISA, IF, IP Wirt: Maus Monoclonal 3E9 unconjugated

anti-Vimentin (VIM) (AA 2-466) antibody
VIM Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 3A1F2 unconjugated

Applikationshinweise

Western blotting: 1/1,000. Immunofluorescence: 1/500. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Handhabung

Avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store the antibody undiluted (in aliquots) at-20 °C.
Plitzko, Havemeyer, Kunze, Clement: "The pivotal role of the mitochondrial amidoxime reducing component 2 in protecting human cells against apoptotic effects of the base analog N6-hydroxylaminopurine." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10126-35, (2015) (PubMed).

Kang, Taldone, Patel, Patel, Rodina, Gozman, Maharaj, Clement, Patel, Brodsky, Young, Chiosis: "Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70." in: Journal of medicinal chemistry, Vol. 57, Issue 4, pp. 1188-207, (2014) (PubMed).

Kirane, Toombs, Ostapoff, Carbon, Zaknoen, Braunfeld, Schwarz, Burrows, Brekken: "Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 18, pp. 5031-42, (2012) (PubMed).
Target

Vimentin (VIM)

Andere Bezeichnung

Vimentin (VIM Produkte)

Hintergrund

Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).Synonyms: VIM

Gen-ID

81818

NCBI Accession

NP_112402

UniProt

P31000

Pathways

Caspase Kaskade in der Apoptose