AKR1A1 Antikörper (C-Term)

Produktnummer ABIN374244

Produktdetails anti-AKR1A1 Antikörper

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser AKR1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: C-DAGHPLYPFN DPY

Spezifität: This antibody detects AKR1A1 / ALDR1 at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig, Cow.
Species reactivity (tested):Human.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_006057.1, NP_697021.1. Genename: AKR1A1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western blot: Approx 38 kDa band observed in Human Placenta and Liver lysates(calculated MW of 36.8 kDa according to NP_006057.1). Recommended concentration: 0.5 - 2 μg/mL. Immunohistochemistry on paraffin sections: Human Kidney shows Brush Border stainingin PCT. Recommended concentration: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu AKR1A1

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Andere Bezeichnung: AKR1A1 / ALDR1 (AKR1A1 Produkte)

Hintergrund: The AKR1A1 gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Alternative splicing of this gene results in two transcript variants encoding the same protein.Synonyms: ALR, Alcohol dehydrogenase [NADP+], Aldehyde reductase, Aldo-keto reductase family 1 member A1

Gen-ID: 10327

NCBI Accession: NP_006057

UniProt: P14550

Pathways: Monocarboxylic Acid Catabolic Process