MXD4 Antikörper (C-Term)

Produktnummer ABIN374270

Produktdetails anti-MXD4 Antikörper

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MXD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GPHCRRLGRP ALS

Spezifität: This antibody detects MAD4 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_006445.1 Genename: MXD4

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.5-2 μg/mL. Approx 22 kDa band observed in human kidney lysates(predicted MW of 22 kDa according to NP_006445). Please note the appearance of thisband was blocked by incubation with the immunising peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu MXD4

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Andere Bezeichnung: MAD4 (MXD4 Produkte)

Hintergrund: MAD4 is a member of the MAD gene family . The MAD genes encode basic helix loop helix leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.Synonyms: MAD-4, MAX dimerization protein 4, MXD4, Max-associated protein 4, Max-interacting transcriptional repressor MAD4

Gen-ID: 10608

NCBI Accession: NP_006445

UniProt: Q14582