Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.5-2 μg/mL. Approx 22 kDa band observed in human kidney lysates(predicted MW of 22 kDa according to NP_006445). Please note the appearance of thisband was blocked by incubation with the immunising peptide. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
MAD4 antikoerper, MST149 antikoerper, MSTP149 antikoerper, bHLHc12 antikoerper, xmad4 antikoerper, mst149 antikoerper, bhlhc12 antikoerper, mstp149 antikoerper, MGC84841 antikoerper, MXD4 antikoerper, 2810410A03Rik antikoerper, Mad4 antikoerper, MAX dimerization protein 4 antikoerper, Max dimerization protein 4 antikoerper, MAX dimerization protein 4 S homeolog antikoerper, microRNA 4800 antikoerper, MXD4 antikoerper, Mxd4 antikoerper, mxd4.S antikoerper, MIR4800 antikoerper, mxd4 antikoerper
Hintergrund
MAD4 is a member of the MAD gene family . The MAD genes encode basic helix loop helix leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.Synonyms: MAD-4, MAX dimerization protein 4, MXD4, Max-associated protein 4, Max-interacting transcriptional repressor MAD4