MYRIP Antikörper (C-Term)

Produktnummer ABIN374340

Produktdetails anti-MYRIP Antikörper

Target: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MYRIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-KDLMEPALES AVMY

Spezifität: This antibody detects MYRIP at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_056275.2 Genename: MYRIP

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1/64000. Western blot: Use at 0.1-0.3 μg/mL. Approx 90 kDa band observed in Human Brain(Amygdala) lysates (Calculated MW of 95.0 kDa according to NP_056275.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris-saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Details zu MYRIP

Target: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Andere Bezeichnung: MYRIP (MYRIP Produkte)

Synonyme: SLAC2-C antikoerper, SLAC2C antikoerper, A230081N12Rik antikoerper, Slac2-c antikoerper, Slac2c antikoerper, MYRIP antikoerper, si:dkey-189e1.4 antikoerper, LOC100156583 antikoerper, myosin VIIA and Rab interacting protein antikoerper, MYRIP antikoerper, Myrip antikoerper, myrip antikoerper

Hintergrund: A molecular complex composed of Rab27A, MYRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles. The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosin VIIa-defective mice.Synonyms: Exophilin-8, Myosin-VIIa- and Rab-interacting protein, Rab effector MyRIP, SLAC2C, SlaC2-c, Slp homolog lacking C2 domains c

Gen-ID: 25924

NCBI Accession: NP_056275

UniProt: Q8NFW9

Pathways: Positive Regulation of Peptide Hormone Secretion