HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (N-Term) Antikörper

Produktnummer ABIN374419

Produktdetails

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects HTATIP2 at N-term.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence AETEALSKLREDFR-C, from the N Terminus of the protein sequence Genename: HTATIP2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western blot: 0,3 - 1,0 μg/mL. Approx 30 kDa band observed in Hela and Human Lunglysates (predicted MW of 27.0 kDa according to NP_006401).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Antigendetails

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Andere Bezeichnung: HTATIP2 (HTATIP2 Produkte)

Substanzklasse: Viral Protein

Hintergrund: TIP30 is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23 H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription. This protein is also known to bind the activation domain of HIV-1 Tat.Synonyms: 30 kDa HIV-1 TAT-interacting protein, CC3, HIV-1 TAT-interactive protein 2, Oxidoreductase HTATIP2, TIP30

Gen-ID: 10553

NCBI Accession: NP_001091990

UniProt: Q9BUP3