Paired Box 3 Antikörper (N-Term)
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- Target Alle Paired Box 3 (PAX3) Antikörper anzeigen
- Paired Box 3 (PAX3)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh)
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Paired Box 3 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequenz
- TTLAGAVPRM M-C
- Spezifität
- This antibody detects PAX3 at N-term. This antibody is expected to recognise all 7 reported human isoforms (as represented by NP_000429.2, NP_039230.1, NP_852122.1,.1 NP_852123.1, NP_852124.1, NP_852125.1 and NP_852126.1).
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat and Cow.
Species reactivity (tested):Human. - Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide from the N Terminus of the protein sequence according to NP_000429.2, NP_039230.1, NP_852122.1,.1 NP_852123.1, NP_852124.1, NP_852125.1, NP_852126.1. Genename: PAX3
- Top Product
- Discover our top product PAX3 Primärantikörper
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- Applikationshinweise
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Peptide ELISA: Antibody Limit Dilution: 1/64000. Western blot: Preliminary experiments gave an approx 30-35 kDa band in Human Kidneylysates at 1 μg/mL. Immunohistochemistry: 3 μg/mL. In paraffin embedded Human Oesophagus showsnuclear staining of cells in the Squamous Epithelium.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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- Target
- Paired Box 3 (PAX3)
- Andere Bezeichnung
- PAX3 (PAX3 Produkte)
- Synonyme
- PAX3 antikoerper, cdhs antikoerper, hup2 antikoerper, pax-3 antikoerper, ws1 antikoerper, xpax3 antikoerper, Pax3 antikoerper, pax3 antikoerper, pax3b antikoerper, xPax3-B antikoerper, CDHS antikoerper, HUP2 antikoerper, WS1 antikoerper, WS3 antikoerper, Pax-3 antikoerper, Sp antikoerper, splotch antikoerper, zgc:92547 antikoerper, paired box 3 antikoerper, paired box 3 L homeolog antikoerper, paired box 3a antikoerper, PAX3 antikoerper, pax3 antikoerper, pax3.L antikoerper, Pax3 antikoerper, pax3a antikoerper
- Hintergrund
- This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.Synonyms: HUP2, Paired box protein Pax-3, Pax-3
- Gen-ID
- 5077
- NCBI Accession
- NP_000429
- UniProt
- P23760
- Pathways
- Sensory Perception of Sound, Tube Formation
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