FOXO3 Antikörper (C-Term)
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- Target Alle FOXO3 Antikörper anzeigen
- FOXO3 (Forkhead Box O3 (FOXO3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Schwein
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser FOXO3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Sequenz
- C-GAKQASSQSW VPG
- Spezifität
- This antibody recognizes FKHRL1/FOXO3A.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Porcine, Bovine.
Species reactivity (tested):Human. - Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide from the C Terminus of the protein sequence according to according to NP_001446.1. Genename: FOXO3
- Top Product
- Discover our top product FOXO3 Primärantikörper
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- Applikationshinweise
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Peptide ELISA: 1/32,000. Western Blot: Approx 90 kDa band observed in human Brain and Heart lysates (calculatedMW of 71.0 kDa according to NP_001446 and NP_963853). Recommended concentration: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FOXO3 (Forkhead Box O3 (FOXO3))
- Andere Bezeichnung
- FOXO3 / FKHRL1 (FOXO3 Produkte)
- Synonyme
- AF6q21 antikoerper, FKHRL1 antikoerper, FKHRL1P2 antikoerper, FOXO2 antikoerper, FOXO3A antikoerper, zgc:92176 antikoerper, wu:fb50g02 antikoerper, wu:fi33f07 antikoerper, Fkhrl1 antikoerper, Foxo3a antikoerper, FoxO3A antikoerper, 1110048B16Rik antikoerper, 2010203A17Rik antikoerper, C76856 antikoerper, Fkhr2 antikoerper, FOXO-3 antikoerper, FOXO3 antikoerper, foxo3a antikoerper, xfoxo3 antikoerper, foxO3 antikoerper, foxO antikoerper, fkhr antikoerper, foxo5 antikoerper, wu:fj65a12 antikoerper, zFkhr antikoerper, forkhead box O3 antikoerper, forkhead box O3A antikoerper, forkhead box O3 L homeolog antikoerper, forkhead box O3b antikoerper, FOXO3 antikoerper, foxo3a antikoerper, Foxo3 antikoerper, foxo3.L antikoerper, foxo3 antikoerper, foxO3 antikoerper, foxo3b antikoerper
- Hintergrund
- FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two tiered mechanism of phosphorylation and acetylation. FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors. It recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. FOXO3a has been shown to induce cell growth arrest to effect tumor suppression and FOXO3A genotype is strongly associated with human longevitySynonyms: AF6q21 protein, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1
- Gen-ID
- 2309
- NCBI Accession
- NP_001446
- UniProt
- O43524
- Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis
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