CD2BP2 Antikörper (N-Term)

Produktnummer ABIN374445

Produktdetails anti-CD2BP2 Antikörper

Target: CD2BP2 (CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CD2BP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: C-PKRKVTFQGV GDE

Spezifität: This antibody recognizes CD2BP2.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Cow.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the N Terminus of the protein sequence according to NP_006101.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32,000. Western Blot: 0.3-1.0 μg/mL. Detects a band of Approx 50 kDa in Human Lymph Node,Thymus and Tonsil lysates (Predicted Molecular Weight: 37.0 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu CD2BP2

Target: CD2BP2 (CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2))

Andere Bezeichnung: CD2BP2 (CD2BP2 Produkte)

Hintergrund: CD2BP2 is an intracellular protein which binds to a site containing two PPPGHR segments within the cytoplasmic region of CD2. Mutagenesis and NMR analysis demonstrated that the CD2 binding region of CD2BP2 includes a 17 amino acid motif also found in several yeast and Caenorhabditis elegans proteins of unknown function. In Jurkat T cells, over expression of the isolated CD2BP2 domain binding to CD2 enhances the production of interleukin 2 on crosslinking of CD2 but not the T cell receptor.Synonyms: CD2 antigen cytoplasmic tail-binding protein 2, CD2 cytoplasmic domain-binding protein, CD2 tail-binding protein, KIAA1178

Gen-ID: 10421, 9606

UniProt: O95400

Pathways: Ribonucleoprotein Complex Subunit Organization