HPS3 Antikörper (C-Term)

Produktnummer ABIN374450

Produktdetails anti-HPS3 Antikörper

Target: HPS3 (Hermansky-Pudlak Syndrome 3 (HPS3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser HPS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PYLLYCSRKK PLT

Spezifität: This antibody recognizes HPS3/Cocoa

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_115759

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: > 1/32,000. Western Blot: 1-3 μg/mL. Detects a band of Approx 110 kDa in A431 cell lysate(Predicted Molecular Weight: 114 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu HPS3

Target: HPS3 (Hermansky-Pudlak Syndrome 3 (HPS3))

Andere Bezeichnung: HPS3 (HPS3 Produkte)

Hintergrund: HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.Synonyms: Hermansky-Pudlak syndrome 3

Gen-ID: 84343

NCBI Accession: NP_115759

UniProt: Q969F9